At least two children were killed and four other civilians wounded in Ghazni province, officials said Thursday.
The provincial acting-governor's spokesman Shafiq Nang confirmed the incident and said that the blast occurred on Wednesday in Deh Yak district when a civilian vehicle hit by a roadside mine.
The victims are members of one family. Nang said.
The injured were taken to a nearby hospital.
No group including the Taliban has yet claimed responsibility.